Mesoceuticals
JeuDérmAdvanced Skincare
About the line
The MESOCEUTICALS family bundles JeuDérm’s injectable preparations for aesthetic medicine: REJUSOME and REJUSOME PLUS with lyophilised exosomes, Crystal PDRN with highly concentrated polynucleotides, the Botox alternative BOTOLUX, the vegan exosome alternative BIOXOME and ULTRA V, liquid polycaprolactone (PCL), the first aesthetic hybrid for long-lasting collagen stimulation. Together they form an arsenal for biorevitalisation, firming and scar-free regeneration.
Effect
Biorevitalisation
PDRN and peptides promote collagen and elastin synthesis in depth.
Collagen stimulation
Liquid PCL forms a 3D matrix for a lifting effect lasting 1–4 years.
Professional
Sterile preparations for intradermal injection, mesoroller and Dermapen.
The products
11 products in detail
Professionals
5 ampoules 5 ml, sterile · Dermapen or mesoroller · three to five treatments, every two weeks
Crystal PDRN
The richest meso concentrate: 6,000 ppm polynucleotides, 2,000 ppm peptides
The richest meso concentrate of the range, sterile, with Sodium DNA as the lead active. Seven peptide groups, eighteen EGF variants and fifteen amino acids in one ampoule, plus three forms of hyaluronic acid and seven minerals: what other houses spread over three products is here in one formula.
Contains among others
Sodium DNA, 6,000 ppm · seven peptide groups, 2,000 ppm, including Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-5 · eighteen EGF variants · fifteen amino acids · three forms of hyaluronic acid · hydrolysed collagen and panthenol · niacinamide, biotin and tocopheryl acetate · zinc gluconate, magnesium and calcium gluconate · adenosine
In the system
Applied with Dermapen or mesoroller by medically licensed practitioners, three to five treatments two weeks apart. The same polynucleotide is in the REFORM AGE DNA Cream in topical form: the link to the home care that follows.
Professionals
2 bottles 5 ml · Dermapen or mesoroller · store at 2 to 8 °C
Botolux
Two components: 6 % Acetyl Hexapeptide-8, 3 % low-molecular hyaluronic acid
The meso concentrate with the shortest formula of the house: 6 % Acetyl Hexapeptide-8 and 3 % low-molecular hyaluronic acid, and nothing else, no extracts, no fragrance. In the brand’s cosmetics the same neuropeptide sits in the ppm range; six percent is a different order of magnitude.
Contains among others
Acetyl Hexapeptide-8 (Argireline), 6 % · low-molecular hyaluronic acid, 3 % · no extracts · no fragrance
In the system
Small molecules spread differently from large ones; when introduced through a needle module, molecular size is no side issue. Belongs in the refrigerator like the REJUSOME two-vial system; topically the house carries the same approach in the O2 Boto Fluid and the DNA Cream.
Professionals
2 bottles 5 ml · Dermapen or mesoroller · store at 0 to 25 °C
BioXome
The vegan concentrate: Acetyl Glutamine in position 1, ferment filtrate with folic acid
A meso concentrate the manufacturer explicitly lists as vegan, in a category that otherwise works with collagen or polynucleotides from salmon milt. First in the formula is Acetyl Glutamine, an acetylated amino acid as a single active; the ferment filtrate with folic acid appears in no other product of the house.
Contains among others
Acetyl Glutamine in position 1 · Bacillus/Folic Acid Ferment Filtrate Extract · peptides, highly concentrated according to the manufacturer · hyaluronic acid · no animal-derived raw materials
In the system
Applied by trained professionals with Dermapen or mesoroller, reserved for medically licensed practitioners. For practices whose clients ask for a vegan formula this is no side argument; on the skin, the ADAPTIVE SKIN line carries the comparable approach.
Professionals
3 ampoules 2 ml · for use by physicians only
Ultra V
Biostimulator of liquid polycaprolactone, not a volume filler, for physicians only
A polycaprolactone-based biostimulator and not a cosmetic product: it is introduced into the skin, not applied onto it. Most PCL products are microspheres in a gel; this one is liquid. PCL and polylactic acid are both biostimulators, not volume fillers; the difference lies in the degradation, PCL degrades more slowly.
Contains among others
Polycaprolactone (PCL) in liquid form · biocompatible · biodegradable · established in medicine as suture material and implant material · full composition requested from the manufacturer
In the system
Beauticians in Germany may not perform invasive procedures, and the preparation is not sold to end customers; the application parameters have been requested from the manufacturer. For the treatment room, LIFT INTENSE, REFORM AGE and REJUSOME work on the skin.
Professionals
2 pre-filled syringes 2.5 ml · for use by physicians only
Calyra Lux 5
Pre-filled syringe with 2.5 ml, the Korean version of the Calyra range, physicians only
A preparation in pre-filled syringes, built for injecting and therefore not a cosmetic product. The Korean version of the Calyra range with 2.5 ml per syringe; the sister product Calyra comes CE-marked from Italy and carries 2 ml. Two countries of origin, two regulatory routes, two supply chains for formally related products.
Contains among others
Composition, indication and application parameters are not available · they belong in the manufacturer’s instructions for use · requested from the supplier
In the system
Exclusively by licensed physicians according to the manufacturer’s instructions for use; not sold to end customers. For the treatment room, the range carries the topical lines LIFT INTENSE, REFORM AGE and REJUSOME.
Professionals
120 mg dry substance + 5 ml solution · Dermapen or mesoroller · mix immediately before use
Vital NAD+
Two components: 120 mg NAD+ as dry substance and 5 ml solution
A two-component concentrate: 120 mg nicotinamide adenine dinucleotide as dry substance and 5 ml solution, combined only immediately before use. What is not permanently stable in aqueous solution is stored dry and dissolved when needed, the same construction principle as REJUSOME and ALA VITA C.
Contains among others
Nicotinamide adenine dinucleotide (NAD+), 120 mg per unit · 5 ml solution · composition of the solution requested from the manufacturer
In the system
Applied by trained professionals with Dermapen or mesoroller; in Germany reserved for medically licensed practitioners. Niacinamide, present in almost every product of the house, is a precursor of NAD+: the link to the skin care.
Professionals
2 bottles 5 ml · Dermapen or mesoroller
Amber Pro
Redermalisant with amber component, the only place in the whole range
A meso concentrate the manufacturer lists as a redermalisant: not one active for one feature, but a preparation for the structure. The name refers to amber, and this component appears nowhere else in the whole range. Peptide set-up and hyaluronic base it shares with the other concentrates of the series.
Contains among others
Amber component, the raw material that gives the name · peptide set-up of the Mesoceuticals series · hyaluronic base · full composition requested from the manufacturer
In the system
The other approach within the series: Crystal PDRN works via polynucleotides, BioXome via ferments, Botolux via a single neuropeptide. Applied by trained professionals with Dermapen or mesoroller, reserved for medically licensed practitioners.
Professionals
2 bottles 5 ml · Dermapen or mesoroller, on the body
Neoslim
The body concentrate of the series: caffeine, carnitine and rutin as the core of the formula
The drainage concentrate of the Mesoceuticals series and the only one intended for the body. The composition is the classic one of body cosmetics: caffeine, carnitine, rutin and lipopeptides. Rutin is the unusual part; the flavonoid from the Japanese pagoda tree is rare in body concentrates.
Contains among others
Caffeine · carnitine · rutin, the flavonoid from the Japanese pagoda tree · lipopeptides
In the system
In the Lipo-Control Physio-Gel, caffeine, carnitine and coenzyme A sit in positions 28 to 30; here they form the core instead of the end of the list. For device work without a needle, the house carries the Lipo-Control and the Drainage Physio-Gel.
Professionals
Ampoule 200 mg lyophilisate · reconstituted, needle or cannula · for use by physicians only
Gloriosafill
41 % poly-L-lactic acid, double freeze-dried: biostimulator, not a volume filler
A polylactic-acid-based biostimulator, 200 mg lyophilisate reconstituted before use, and not a cosmetic product. 41 % poly-L-lactic acid, 24 % carboxymethylcellulose, 35 % mannitol: the composition is complete. Unlike hyaluronic acid, polylactic acid does not fill immediately; the material is degraded over months.
Contains among others
Poly-L-lactic acid (PLLA) 41 %, 82 mg · carboxymethylcellulose (CMC) 24 %, 48 mg · mannitol 35 %, 70 mg · double freeze-dried · stored at room temperature, shelf life two years
In the system
The manufacturer specifies injection deep into the skin or the subcutaneous layer with a needle or cannula, followed by massage; not Dermapen, MTS or needle-free application. For physicians only, not sold to end customers.
Professionals
Vial 1: 20 mg powder, vial 2: 5 ml solution · mesoroller, Dermapen or intradermal · freshly mixed, store at 2 to 8 °C
Rejusome
Two vials, freeze-dried: peptides in positions 4 to 13 of vial 1
The sterile two-component system of the line: 20 mg freeze-dried exosome powder in vial 1, 5 ml solution in vial 2, mixed immediately before use. Peptides break down in aqueous solution, not in dry form; that is why positions 4 to 13 of vial 1 carry peptides, including sh-Polypeptide-76, which is new to the range.
Contains among others
Exosomes, 74,000 ppm in vial 1 · peptides, 2,000 ppm: sh-Polypeptide-76, sh-Oligopeptide-1 and -2, sh-Polypeptide-1 and -3 · Copper Tripeptide-1 · Acetyl Hexapeptide-8 · Nonapeptide-1 · Palmitoyl Tetrapeptide-7 and Palmitoyl Tripeptide-1 · seventeen free amino acids in both vials · sodium hyaluronate · Sodium DNA, 1,000 ppm in vial 2 · tranexamic acid, ascorbyl glucoside and niacinamide in vial 2
In the system
Only Professional Use: the manufacturer names mesoroller, Dermapen and intradermal injection; use within three hours of mixing, a course of three to five treatments two to three weeks apart. 2 to 8 °C is a storage condition, not a recommendation.
Professionals
Ampoule 2 ml, sterile · mesoroller, Dermapen or intradermal · three to five treatments, every two weeks
Rejusome Plus
27 billion exosomes per millilitre, the most concentrated preparation of the house
A sterile exosome preparation in a 2 ml ampoule and not a cosmetic product: the manufacturer describes it for intradermal use in regenerative medicine. 27 billion exosomes per millilitre, laboratory-grown and highly purified; the Exo Boost Cream of the same line, with 10,000 ppm plant exosomes, is in a different order of magnitude.
Contains among others
Laboratory-grown exosomes, 27 billion per millilitre · sterile and highly purified · fields of use according to the manufacturer: dermatology, cosmetology, trichology · store at 2 to 8 °C · full composition not available
In the system
Exclusively by medically licensed practitioners, physicians and licensed Heilpraktiker; not sold to end customers. The Exo Boost care works with the same basic idea in a form that stays on the skin: serum, cream, eye cream and mask.