Acnocell

Four articles are enough to start: Mild Cleanser (250 ml) for cleansing, Treatment Toner (100 ml), Treatment Gel (100 ml) and Treatment Emulsion (100 ml). That gives you a complete home-care routine on the shelf without committing to nine article numbers straight away. If you also want to work in the treatment room, add Clay Mask (250 ml) and Treatment Gel (150 ml). The rest can be listed at any time once you see what your clients ask for.

Four articles carry the print “FOR PROFESSIONALS ONLY” and are thus clearly professional goods: Treatment Toner (250 ml), Treatment Gel (150 ml), Treatment Emulsion (150 ml) and Clay Mask (250 ml). For your client’s handbag there are the same three care products in 100 ml. Mild Cleanser (250 ml) and Multi-Acid Pad (50 pads) do not carry this print and can be used in both channels.

The range comprises nine article numbers and six products, but you do not have to carry all nine. A closed routine already results from cleanser, toner, gel and emulsion, i.e. four items. Multi-Acid Pad and Clay Mask are the two additions with which you later bring depth to the shelf. That keeps the first order lean and the advice complete nonetheless.

It can be counted exactly for the Multi-Acid Pad: 50 soaked pads, one pad in the evening for face and neck, which gives 50 applications. For the bottles the range depends on the amount applied; the Treatment Gel is used as a spot treatment and therefore lasts considerably longer than the emulsion applied all over. The larger packs are intended for the treatment room: toner 250 ml, gel and emulsion 150 ml each, Clay Mask 250 ml. With the pad, count on the most reliable repurchase interval of your shelf.

Through the content, not the label: Treatment Gel and Treatment Emulsion carry 330 ppm peptides directly on the pack, the Mild Cleanser 50 ppm, numbers the manufacturer has printed and which we pass on exactly as they are. The peptide building blocks are named in the INCI: Copper Tripeptide-1, Hexapeptide-61 Dimer and, in gel and emulsion, Nonapeptide-1. Behind them is a granted Korean patent (KR 10-1689878, holder Cellicon Lab Inc., granted on 20 December 2016, term until 2034) on a dimer peptide and Copper Tripeptide-1. The technology was developed by Prof. Soung Min-Gyu, founder of Cellicon Lab; it is manufactured in South Korea by Virta-Med Korea Co., Ltd.

The Multi-Acid Pad sets the clearest rhythm: 50 pads at one application per evening means around seven weeks, after which a repurchase is due. The Clay Mask is intended as a professional product for one to two applications per week and thus carries your treatment calendar. Toner, gel and emulsion are used twice daily. A follow-up contact after four weeks and a second after eight weeks has proven itself in accompanying such routines; this rhythm also corresponds to the control scheme of the Sechenov investigation (day 0, 30 and 60).

The line is built exactly for that: for every treatment-room size there is the identical product as home care in 100 ml (toner 250/100 ml, gel 150/100 ml, emulsion 150/100 ml). What you apply on the couch, the client can therefore continue unchanged at home; you are not selling a second brand but the continuation of your own treatment. That makes the sales argument short and credible.

Yes. According to the manufacturer, the Treatment Gel is intended as a contact medium for device techniques including laser and can be combined with LED. For the treatment room there is the 150 ml pump bottle. The gel carries 330 ppm peptides, niacinamide is in position 3 of the INCI list. So you use one pack for treatment and retail at the same time.

In four steps: lather the Mild Cleanser and rinse, apply the Treatment Toner with a cotton pad and massage in lightly; it contains a light emulsion system and is therefore not wiped off. Then the Treatment Gel as a spot treatment, followed by the Treatment Emulsion all over; its pack expressly says “Recommended to be applied after Treatment Gel”. The Multi-Acid Pad is added once daily in the evening, the Clay Mask once or twice a week. Your beautician discusses before the first application which steps suit the respective skin.

You may report the design and scope of the investigations as fact: at Sechenov University Moscow, an investigation with 30 participants over 60 days ran from November 2016 to January 2017 under Prof. O. Yu. Olisova and Prof. E. S. Snarskaya, measured with sebumetry and corneometry on the Cutometer MPA 580. In Korea two further series ran: at Chonnam National University Hospital with 29 participants over twelve weeks and at Chungnam National Medical University with 320 participants over four weeks against placebo. Stick to design, location and scope, and do not cite result figures or statements on tolerability. These investigations ran in Russia and South Korea, where such preparations are categorised differently; in the EU, ACNOCELL is a cosmetic product for oily, blemish-prone skin. The most robust evidence in the conversation is the pack itself anyway: printed ppm figures, INCI list and manufacturer details.

First lather the Mild Cleanser and rinse, then apply the Treatment Toner (250 ml) with a cotton pad. Then the Treatment Gel (150 ml) on the affected areas and over it the Treatment Emulsion (150 ml) all over; the order is printed on the pack: “Recommended to be applied after Treatment Gel”. The Clay Mask complements the treatment once or twice a week: leave on for 15 minutes, let it dry, rinse. This gives you a clear procedure you can run identically at every appointment.

Morning and evening: Mild Cleanser, then Treatment Toner (100 ml), the Treatment Gel (100 ml) as a spot treatment and over it the Treatment Emulsion (100 ml) all over; gel and emulsion are not rinsed off. In the evening, after cleansing, a Multi-Acid Pad can additionally be used for face and neck. All three home-care sizes correspond to the professional products, so the client continues at home exactly what you set up at the institute.

Yes. According to the manufacturer, the Treatment Gel is intended as a contact medium for device techniques including laser and can be combined with LED. It carries 330 ppm, printed on bottle and box, and lists niacinamide in position 3 of 50 and witch hazel in position 5. That gives you a contact medium that not only glides but continues your active routine during the appointment.

The Clay Mask (250 ml) stays on the skin for 15 minutes, may dry and is then rinsed off, once or twice a week. Kaolin is in position 2, Talc in 4 and Titanium Dioxide in 5, niacinamide follows in position 28 of 48; at the end of the list are sh-Oligopeptide-1 and -2, sh-Polypeptide-1 and -22 and Copper Tripeptide-1. It is marked as a professional product with the print “FOR PROFESSIONALS ONLY” and works well as the visible highlight of the treatment.

One pad daily in the evening for face and neck; the jar contains 50 soaked pads (100 ml). According to the manufacturer, the total acid content is around 7 % with 3.0 % tranexamic acid, 2.0 % mandelic acid, 1.4 % glycolic acid, 0.5 % citric acid and 0.2 % salicylic acid at pH 3.5, accompanied by ceramide NP in position 32 and 16 plant extracts. Because application is intended for the evening, sun protection belongs in the daytime routine, as with any acid care.

With a cotton pad, twice daily, massaging in rather than wiping dry. The toner is built as a light emulsion system via hydrogenated lecithin, Sorbitan Olivate and Cetearyl Olivate, so a care layer remains on the skin that you work in. With only 26 INCI positions, niacinamide in position 4, panthenol, dipotassium glycyrrhizate, Copper Tripeptide-1 (pos. 19) and Hexapeptide-61 Dimer (pos. 26), it is the shortest formula of the line.

The large packs are professional goods: toner 250 ml, gel 150 ml, emulsion 150 ml and Clay Mask 250 ml carry the print “FOR PROFESSIONALS ONLY”. For the client there are toner, gel and emulsion in 100 ml with the same formula. So you work economically at the institute and hand over the identical care for home, so the treatment continues between appointments.

In the preliminary talk you clarify what suits the skin and start with the basics: Mild Cleanser, Treatment Toner and Treatment Emulsion, with the Treatment Gel as a spot treatment. You add the Multi-Acid Pad once the basic routine is firmly in place. Plan fixed check-up appointments: in the investigations, assessment was done at rhythms of 2, 4, 8 and 12 weeks (Chonnam National University Hospital) or on day 0, 30 and 60 (Sechenov University Moscow); photo documentation at this rhythm makes the development visible for the client.

Start lean with cleanser, toner and emulsion and introduce the Multi-Acid Pad slowly instead of using it daily straight away. The Treatment Emulsion is well suited for this: centella is represented three times, as Asiaticoside (pos. 27), Centella Asiatica Extract (pos. 28) and Madecassoside (pos. 30), plus Houttuynia cordata and panthenol. Clarify known intolerances in the preliminary talk and, if the starting situation is uncertain, work with a small-area pre-test. If the skin reacts to the change, reduce the frequency or pause the acid and stay with the basics until the skin is calm.

The line covers the routine completely from cleansing through toner, gel and emulsion to the mask and is coordinated in order and structure; the pack print of the emulsion expressly refers to application after the gel. Therefore keep third-party products sparse in the starting phase, so the assessment at the check-up stays unambiguous and you know what the skin responds to. The peptide components Copper Tripeptide-1, Hexapeptide-61 Dimer and Nonapeptide-1 (the latter only in gel and emulsion) are then used in the sequence intended by the manufacturer. For device appointments the Treatment Gel remains the contact medium.

Peptides are short chains of amino acids; the brand works among others with Copper Tripeptide-1, Hexapeptide-61 Dimer, Nonapeptide-1, glutathione and the five amino acids alanine, arginine, glycine, glutamic acid and serine. ppm means “parts per million”; 330 ppm corresponds to 0.033 %, an order of magnitude at which percentages would become unwieldy. Exactly these numbers are on the packaging: 330 ppm on Treatment Gel (bottle and box) and Treatment Emulsion (both packs), 50 ppm on the bottle of the Mild Cleanser. Toner, Multi-Acid Pad and Clay Mask carry no ppm figure on the pack; there we deliberately give no number.

Acnotide is the manufacturer’s brand name for the amino-acid complex of alanine, arginine, glycine, glutamic acid and serine. Four of these amino acids (alanine, arginine, glycine and serine) are expressly the subject of the granted Korean patent KR 10-1689878. The manufacturer also uses further complex names: Wrinkle Free J316 for Hexapeptide-61 Dimer, Demelaxyl for Nonapeptide-1, plus Triple M Complex and MultiEX for the plant part. On the label you will find these substances under their INCI names, not under the brand name.

GHK-Cu is the copper tripeptide of glycine, histidine and lysine, declared on the label as Copper Tripeptide-1. It is among the longest-described cosmetic peptides and at the same time one of the expressly patent-protected components of the formula concept (KR 10-1689878). In the series you will find it in the Treatment Toner in position 19 of only 26 positions and in the Clay Mask in the peptide-rich part of the list together with sh-Oligopeptide-1 and -2 and sh-Polypeptide-1 and -22.

Because it is used there in a leading quantity: in the Treatment Toner position 4 of 26, in the Treatment Gel position 3 of 50, in the Treatment Emulsion position 3 of 54. INCI lists are sorted in descending order by proportion down to 1 %; such an early position is therefore a robust statement about the amount used. For the consultation, niacinamide is the anchor for the topics of sebum shine, matte skin and even complexion. In the Clay Mask it is in position 28; the Mild Cleanser and the Multi-Acid Pad contain none, which is useful to know when planning the routine.

Tranexamic acid is in position 3 of the overall list and is thus the leading of the six acids by quantity; it is followed by mandelic acid, glycolic acid, citric acid, salicylic acid (position 14) and oleanolic acid. According to the manufacturer (no number is on the pack), it is 3.0 % tranexamic acid, 2.0 % mandelic acid, 1.4 % glycolic acid, 0.5 % citric acid and 0.2 % salicylic acid, together around 7 % total acid at pH 3.5. The focus is thus not on maximum removal by a single strong acid but on a staggered profile aimed at an even complexion. One pad is applied in the evening to face and neck.

Ceramide NP is in position 32 in the Multi-Acid Pad and is part of a deliberately accompanying remaining profile: added are Centella asiatica, Roman chamomile (Anthemis nobilis), Houttuynia cordata, sesame extract and 16 plant extracts in total. Ceramides belong to the skin’s own lipid classes and in an acid formula are the classic counterweight to the exfoliating part. For your clients that means: one pad daily in the evening, easy to integrate into an evening routine. What suits the respective skin and at what rhythm, the beautician discusses before the first application.

Granted is KR 10-1689878, holder Cellicon Lab Inc., Daejeon, filed on 28 August 2014, granted on 20 December 2016, term until 2034. Protected are the dimer peptide [Lys-Thr-X-Lys-Ser-Cys]₂, Copper Tripeptide-1 (Gly-His-Lys with copper) and the amino acids alanine, arginine, glycine and serine. In addition there is application WO 2023/191148 A1 (not yet a granted patent) on a skin-permeable peptide of twelve amino acids, technology name DermiShuttle, priority 31 March 2022, with transport examples from lidocaine and caffeine to collagen 300 kDa and hyaluronic acid 800 kDa. Cellicon Lab states 26 patents and 40 registered peptides; in sales we therefore speak of patented active technologies rather than a verified total number. A patent protects a composition; it is not proof of efficacy and is not used by us as such.

At Sechenov University Moscow, Clinic for Skin and Venereal Diseases, an investigation with 30 participants (15 m, 15 f) aged 14 to 25 ran from November 2016 to January 2017 under Prof. Dr. O. Yu. Olisova and Prof. Dr. E. S. Snarskaya over 60 days with three dates on day 0, 30 and 60, with defined inclusion and exclusion criteria, prior allergy test and written consent. Measurement was by sebumetry and corneometry with the Cutometer MPA 580, microbiological contact-plate examination and the quality-of-life index DLQI according to Finlay. Added to this are Chonnam National University Hospital (29 participants, avg. 22 years, 12 weeks, photo documentation after 2, 4, 8 and 12 weeks) and Chungnam National Medical University (320 participants, avg. 22.6 years, 4 weeks, against placebo). Important for classification: these investigations ran in Russia and South Korea, where such preparations are categorised differently and the endpoints referred to a clinical condition. In the EU, ACNOCELL is a cosmetic product. We therefore reproduce design and methodology, but no result or tolerability figures; those would be inadmissible as a statement about our product.

In the Treatment Emulsion, Asiaticoside is in position 27, Centella Asiatica Extract in position 28 and Madecassoside in position 30, i.e. the whole extract plus two isolated individual substances, placed in immediate proximity. Instead of one extract alone, the formula thus works both with the plant spectrum and with the two best-characterised triterpene components. This is complemented by Houttuynia cordata in position 39. The emulsion is applied all over; the pack expressly recommends application after the Treatment Gel.

Three numbers are on the pack: 50 ppm on the bottle of the Mild Cleanser, 330 ppm on Treatment Gel (bottle and box) and 330 ppm on the Treatment Emulsion (both packs). Striking is the difference between the rinse-off cleansing product and the two leave-on products that stay on the skin: the gel as a spot treatment, the emulsion all over on top, according to the pack recommendation in exactly this order. The manufacturer gives no reason for the gradation; we therefore only reproduce the printed values. Toner, Multi-Acid Pad and Clay Mask carry no ppm figure on the pack; there we deliberately give no number.

The order follows the consistency: first the Mild Cleanser (250 ml) to cleanse and rinse, then the Treatment Toner (100 ml) with a cotton pad, then the Treatment Gel (100 ml) as a spot treatment and finally the Treatment Emulsion (100 ml) all over. The emulsion pack even states this sequence expressly: “Recommended to be applied after Treatment Gel”. You use the Multi-Acid Pad in the evening after cleansing. Your beautician puts together the order that suits your skin.

Cleanser, toner, gel and emulsion are intended for use twice daily, morning and evening. The Multi-Acid Pad belongs exclusively in the evening routine, one pad daily for face and neck. So you have a short routine in the morning and the somewhat more extensive one in the evening.

The complete routine takes only a few minutes. The cleanser is lathered and rinsed off, the toner applied with a cotton pad and massaged in lightly; it contains a light emulsion system with Cetearyl Olivate and Sorbitan Olivate and is therefore massaged in rather than wiped off. Gel and emulsion stay on the skin and are not rinsed off.

Skincare shows over weeks, not days, and how quickly and whether something shows differs from skin to skin; nobody can guarantee you a particular result at a particular time. More important than counting days is that you use the routine regularly and in the intended order: cleanser, toner, gel as a spot treatment, emulsion all over, in the evening additionally the Multi-Acid Pad. Arrange fixed check-up appointments with your beautician; she often sees changes in the skin in comparison earlier than you do in the mirror and adjusts the routine if needed.

Yes, the series is built so that you can replace or add individual steps; cleansing, toner, spot gel and emulsion cover the classic routine. Which of your current products you keep and which you replace, your beautician discusses with you before the first application. She knows the formulations and puts together a combination that suits your skin and your habits.

Starting with one or two products is easily possible; many begin with the Mild Cleanser and the Treatment Toner. The Treatment Gel is suited for spot application, the Treatment Emulsion for all-over care afterwards. The home-care sizes are toner (100 ml), gel (100 ml) and emulsion (100 ml); your beautician recommends what makes sense to start with and what to add later.

One pad daily in the evening, for face and neck; the jar contains 50 soaked pads. Contained are tranexamic acid, mandelic acid, glycolic acid, citric acid, salicylic acid and oleanolic acid as well as ceramide NP and 16 plant extracts, including Centella asiatica and Roman chamomile. According to the manufacturer, the total acid content is around 7 % at pH 3.5. Whether daily or at longer intervals is right for you, your beautician clarifies at the first appointment.

Yes. The Treatment Gel is applied as a spot treatment and the Treatment Emulsion all over on top; neither is rinsed off. Let the emulsion absorb briefly, then you can apply your make-up as usual. In the morning, the time you let pass between care and make-up anyway is usually enough.

The Multi-Acid Pad contains 50 pads; at one pad per evening that is around seven weeks. The Mild Cleanser comes in the 250 ml bottle; toner, gel and emulsion are available as home-care sizes of 100 ml each. The gel is applied only as a spot treatment and is correspondingly economical, while cleanser and toner are used twice daily.

That is exactly what the home-care sizes are for: toner, gel and emulsion at 100 ml each, plus the Mild Cleanser and the Multi-Acid Pads. The large packs of toner, gel and emulsion and the Clay Mask carry the print “FOR PROFESSIONALS ONLY” and stay in the treatment room; the mask is a professional product and part of your appointment. So your home routine and the treatment at the institute work together, and your beautician sees at the next appointment how your skin has developed.

ACNOCELL is built around peptides; the labels list among others Copper Tripeptide-1, Hexapeptide-61 Dimer and, in gel and emulsion, Nonapeptide-1. For the Treatment Gel and the Treatment Emulsion the peptide content of 330 ppm is printed directly on the pack, for the Mild Cleanser 50 ppm, so you can read what you are dealing with. Behind the formula is a granted Korean patent (KR 10-1689878, holder Cellicon Lab Inc.). And: you do not get the line anonymously from the shelf but with your beautician’s assessment of what suits your skin and in what order to use the steps.

Because that is where they are developed and produced: the manufacturer according to the label is Virta-Med Korea Co., Ltd. in Daejeon, every pack carries the print “MADE IN KOREA”. The peptide technologies come from the research company Cellicon Lab, also in Daejeon. Korea is known for skincare with a high focus on actives, and ACNOCELL is an example of this, designed for oily and blemish-prone skin.

The developer is Prof. Soung Min-Gyu, with a doctorate in organic chemistry from the University of Tokyo and a postdoctorate at the Pacific Northwest Research Institute in Seattle. He founded both the research company Cellicon Lab and the brand Jeu’Demeure, which appears internationally as JeuDérm; the name comes from the French, from “Jeunesse” and “Demeure”, roughly “stay young”. Cellicon Lab states 26 patents and 40 registered peptides. The formulas have also been investigated at universities in Russia and South Korea; in the EU the products are cosmetic products.

That is the brand emblem of the line, “JeuDérm · PEPTIDE THERAPY · EXPERT”, i.e. a name, not a statement about a treatment. It names the focus of the formulas: peptides that are listed individually on the labels, such as Copper Tripeptide-1, Hexapeptide-61 Dimer and Nonapeptide-1, plus glutathione and five amino acids. The manufacturer groups these building blocks under its own names such as Acnotide or Wrinkle Free J316. ACNOCELL is and remains a cosmetic care product.

ppm means “parts per million”; 330 ppm corresponds to 0.033 % peptide content. This number is on the Treatment Gel on bottle and box and on the Treatment Emulsion on both packs; the Mild Cleanser carries 50 ppm on the bottle. Peptides act in very small amounts, so these are not low values but usual orders of magnitude for such actives. On the toner, the pad and the mask no number is deliberately printed; we only name what is actually on the pack.

This print is on the treatment-room sizes intended for work during the treatment: Treatment Toner 250 ml, Treatment Gel 150 ml, Treatment Emulsion 150 ml and the Clay Mask 250 ml. Of toner, gel and emulsion there is a 100 ml version each for home: same formula, smaller pack. The mask remains a purely professional product and is part of your treatment at the appointment.

Because the line consists of several coordinated steps and the selection depends on your skin type, which can be advised on but not decided at the shelf. Your beautician discusses before the first application which products suit your skin, in what order and how often. You then take the home-care sizes of toner, gel and emulsion home with you so that the care continues between appointments.

Yes. What matters is not age but the skin condition: the line is designed for oily and blemish-prone skin, and that exists at any age. The formulas are built around peptides listed individually on the labels (Copper Tripeptide-1, Hexapeptide-61 Dimer, Nonapeptide-1 in gel and emulsion), plus niacinamide in third place in gel and emulsion and moisture-binding substances such as sodium hyaluronate and panthenol. The result the line is aimed at is an even, matte skin appearance. Your beautician looks at your skin and puts together the suitable sequence for you, including whether an additional care makes sense.

The Multi-Acid Pad contains not one acid but six, in this order of declaration: tranexamic acid, mandelic acid, glycolic acid, citric acid, salicylic acid and oleanolic acid. According to the manufacturer, the total acid content is around 7 % at pH 3.5, with 3.0 % tranexamic acid and 2.0 % mandelic acid as the largest shares. Added are ceramide NP and 16 plant extracts, including Centella asiatica and Roman chamomile, caring companions alongside the acids. A jar contains 50 soaked pads; you use one pad in the evening for face and neck.

The products are designed as a chain and build on one another: Mild Cleanser for cleansing (its surfactant system is based on Laureth-1 Phosphate, Lauryl Phosphate and Cocamidopropyl Betaine), in the evening the Multi-Acid Pad, then the Treatment Toner with niacinamide in position 4 of 26, the Treatment Gel as a spot treatment and over it the Treatment Emulsion; its pack expressly says “Recommended to be applied after Treatment Gel”. Once or twice a week the Clay Mask is added, usually at the appointment in the treatment room. So the skin gets the care steps in the order intended by the manufacturer. Your beautician agrees with you what to start with and when to extend.